Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 13/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | CD74 | P04233 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20400756 | 0.91 | ADORA2A (0.48) | ADORA2AADORA2BKLKB1CD74MIF | |
| SCHEMBL20400183 | 0.87 | ADORA2A (0.52) | ADORA2AADORA2BKLKB1CD74MIF | |
| SCHEMBL20416884 | 0.86 | ADORA2A (0.55) | ADORA2AADORA2BKLKB1CD74MIF | |
| SCHEMBL29653564 | 0.86 | ADORA2A (0.55) | ADORA2AADORA2BKLKB1CD74MIF | |
| SCHEMBL20436613 | 0.86 | ADORA2A (0.47) | ADORA2AADORA2BKLKB1CD74MIF | |
| SCHEMBL20436604 | 0.85 | ADORA2A (0.51) | ADORA2AADORA2BKLKB1 | |
| SCHEMBL20416992 | 0.84 | ADORA2A (0.45) | ADORA2AADORA2BKLKB1CD74MIF | |
| SCHEMBL20400588 | 0.84 | UCHL5 (0.55) | ADORA2AADORA2BKLKB1CD74MIF | |
| SCHEMBL20400757 | 0.84 | ADORA2A (0.52) | ADORA2AADORA2BKLKB1CDC7DAPK3 | |
| SCHEMBL30400781 | 0.84 | UCHL5 (0.55) | ADORA2AADORA2BKLKB1CD74MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310082-A2 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | Arcus Biosciences, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |