SCHEMBL27034226

SCHEMBL27034226

Cc1nc(C(F)(F)F)ccc1S(=O)(=O)NC1CC2(C1)CN(C1CCOCC1)C2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 2/20 0.36
▸ HTT P42858 2/20 0.35
▸ FPR1 P21462 2/20 0.33
▸ PIK3CD O00329 1/20 0.33
▸ PIK3CA P42336 1/20 0.33
▸ PIK3CB P42338 1/20 0.33
▸ MTOR P42345 1/20 0.33
▸ PIK3CG P48736 1/20 0.33
▸ PIK3C3 Q8NEB9 1/20 0.33
▸ PTGS1 P23219 1/20 0.33
▸ BRD4 O60885 1/20 0.33
▸ TRPV4 Q9HBA0 1/20 0.33
▸ GAA P10253 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ WNT3 P56703 2/20 0.32
▸ SFRP1 Q8N474 2/20 0.32
▸ HDAC4 P56524 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ IRAK4 Q9NWZ3 1/20 0.32
▸ KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27070111 0.86 SFRP1 (0.39) PTGS2WNT3SFRP1KMT2A
SCHEMBL25370762 0.82 TRPV4 (0.41) PTGS2PTGS1TRPV4KMT2AKCNH2
SCHEMBL25369092 0.80 TRPV4 (0.40) TRPV4KMT2AKCNH2HRH3CNR2
SCHEMBL27070110 0.78 PDE9A (0.32) PTGS2KCNH2KCNK3
SCHEMBL27034291 0.78 KMT2A (0.42) PIK3CDPIK3CAPIK3CBMTORPIK3CG
SCHEMBL27034107 0.78 TRPV4 (0.40) PTGS2PTGS1TRPV4GAA
SCHEMBL25370191 0.77 TRPV4 (0.39) PTGS2TRPV4KMT2AKCNH2
SCHEMBL25371528 0.77 TRPV4 (0.39) TRPV4KMT2AKCNH2HRH3
SCHEMBL27034269 0.77 SFRP1 (0.42) BRD4WNT3SFRP1
SCHEMBL25370851 0.77 TRPV4 (0.40) PTGS2FPR1PIK3CATRPV4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4558481-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-28 — — EP claimed
CN-119855809-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-18 — — CN claimed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 — — WO claimed
EP-4558481-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-28 — — EP disclosed
CN-119855809-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-18 — — CN disclosed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 — — WO disclosed
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