Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27034226 | 0.78 | PTGS2 (0.36) | PTGS2KCNK3KCNH2 | |
| SCHEMBL27070113 | 0.75 | IDH1 (0.40) | IDH1IDH2 | |
| SCHEMBL26065407 | 0.74 | LRRK2 (0.31) | LRRK2TLR9TLR8TLR7KCNH2 | |
| SCHEMBL26064896 | 0.72 | HTR2A (0.33) | LRRK2PTGS2TLR9TLR8TLR7 | |
| SCHEMBL27346362 | 0.72 | KCNH2 (0.32) | PDE9ALRRK2PTGS2IDH2KCNH2 | |
| SCHEMBL26065534 | 0.72 | PDE9A (0.31) | PDE9AIDH1IDH2 | |
| SCHEMBL25370762 | 0.71 | TRPV4 (0.41) | PTGS2KCNH2 | |
| SCHEMBL27070242 | 0.71 | HDAC4 (0.36) | — | |
| SCHEMBL26066088 | 0.71 | IRAK4 (0.33) | PDE9A | |
| SCHEMBL26066127 | 0.71 | KCNH2 (0.32) | PDE9AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020156-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-25 | — | — | WO | disclosed |