SCHEMBL27034397

SCHEMBL27034397

Cn1nc(C(F)(F)F)cc1S(=O)(=O)N1CC2(CC(N3CCOCC3)C2)C1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 1/20 0.37
▸ TACR2 P21452 1/20 0.33
▸ HPGD P15428 1/20 0.32
▸ PDE4B Q07343 1/20 0.32
▸ KDM2B Q8NHM5 1/20 0.32
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ RORC P51449 2/20 0.31
▸ LRRK2 Q5S007 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ NPC1 O15118 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ PIK3CD O00329 1/20 0.30
▸ JAK2 O60674 1/20 0.30
▸ HSD11B1 P28845 1/20 0.30
▸ GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27034537 0.92 CTSK (0.39) CTSKTACR2HPGDPDE4BMEN1
SCHEMBL27034422 0.92 CTSK (0.39) CTSKTACR2HPGDPDE4BMEN1
SCHEMBL27034398 0.92 CTSK (0.39) CTSKTACR2HPGDPDE4BMEN1
SCHEMBL26027581 0.91 CTSK (0.38) CTSKTACR2HPGDPDE4BMEN1
SCHEMBL27034404 0.88 CTSK (0.37) CTSKNPC1RAB9A
SCHEMBL27034387 0.87 CTSK (0.38) CTSK
SCHEMBL27034372 0.86 CTSK (0.37) CTSKTACR2HPGDPDE4B
SCHEMBL27034369 0.86 CTSK (0.37) CTSKTACR2HPGDPDE4B
SCHEMBL27070068 0.85 HPGD (0.46) CTSKHPGDKDM2BMEN1KMT2A
SCHEMBL25371880 0.84 CTSK (0.37) CTSKHPGDMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4558481-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-28 — — EP claimed
CN-119855809-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-18 — — CN claimed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 — — WO claimed
EP-4558481-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-28 — — EP disclosed
CN-119855809-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-18 — — CN disclosed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 — — WO disclosed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 — — WO disclosed
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