Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | EBP | Q15125 | 2/20 | 0.37 |
| ▸ | DHCR7 | Q9UBM7 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26064882 | 0.91 | MEN1 (0.39) | HPGDALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL26027581 | 0.86 | CTSK (0.38) | HPGDALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL27034397 | 0.85 | CTSK (0.37) | HPGDALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL27346368 | 0.84 | CTSK (0.39) | HPGDALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27346508 | 0.84 | CTSK (0.39) | HPGDALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27034422 | 0.84 | CTSK (0.39) | HPGDALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL27034537 | 0.84 | CTSK (0.39) | HPGDALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL27034398 | 0.84 | CTSK (0.39) | HPGDALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL26065952 | 0.83 | MEN1 (0.38) | HPGDALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL25363339 | 0.83 | CTSK (0.38) | HPGDALDH1A1KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020156-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-25 | — | — | WO | disclosed |