SCHEMBL27034422

SCHEMBL27034422

Cn1nc(C(F)(F)F)cc1S(=O)(=O)N1CC2(CCC(N3CCOCC3)C2)C1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 1/20 0.39
▸ TACR1 P25103 2/20 0.35
▸ RORC P51449 2/20 0.35
▸ HDAC4 P56524 2/20 0.33
▸ TACR2 P21452 1/20 0.33
▸ HPGD P15428 1/20 0.32
▸ PDE4B Q07343 1/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CHRM4 P08173 2/20 0.31
▸ CHRM1 P11229 2/20 0.31
▸ CHRM2 P08172 1/20 0.31
▸ CHRM5 P08912 1/20 0.31
▸ LRRK2 Q5S007 1/20 0.31
▸ USP5 P45974 1/20 0.31
▸ PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27034398 1.00 CTSK (0.39) CTSKTACR1RORCHDAC4TACR2
SCHEMBL27034537 1.00 CTSK (0.39) CTSKTACR1RORCHDAC4TACR2
SCHEMBL27034397 0.92 CTSK (0.37) CTSKRORCTACR2HPGDPDE4B
SCHEMBL26027581 0.87 CTSK (0.38) CTSKRORCTACR2HPGDPDE4B
SCHEMBL27034456 0.86 MEN1 (0.35) HDAC4TACR2HPGDMEN1KMT2A
SCHEMBL27034331 0.86 MEN1 (0.35) HDAC4TACR2HPGDMEN1KMT2A
SCHEMBL27034307 0.86 MEN1 (0.35) HDAC4TACR2HPGDMEN1KMT2A
SCHEMBL27070068 0.84 HPGD (0.46) CTSKHPGDMEN1KMT2AALDH1A1
SCHEMBL25370768 0.83 CTSK (0.37) CTSKHPGDPDE4BMEN1KMT2A
SCHEMBL27034424 0.83 CHRM4 (0.35) TACR2HPGDMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4558481-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-28 — — EP claimed
CN-119855809-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-18 — — CN claimed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 — — WO claimed
EP-4558481-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-28 — — EP disclosed
CN-119855809-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-18 — — CN disclosed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 — — WO disclosed
WO-2024020156-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-25 — — WO disclosed
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