Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035286 | 0.80 | NPC1 (0.45) | ALDH1A1MAPTNPC1GAARAB9A | |
| SCHEMBL27035144 | 0.79 | PTGES (0.44) | ALDH1A1MAPTNPC1RAB9AHTT | |
| SCHEMBL27139353 | 0.77 | NPC1 (0.43) | ALDH1A1MAPTNPC1GAARAB9A | |
| SCHEMBL27034944 | 0.74 | HTR1A (0.48) | ALDH1A1MAPTNPC1GAARAB9A | |
| SCHEMBL1544070 | 0.63 | CA2 (0.47) | ALDH1A1NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL12092543 | 0.63 | HTT (0.61) | NPC1RAB9AHTTTHRBLMNA | |
| SCHEMBL27035204 | 0.62 | SMN1; SMN2 (0.56) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL12088789 | 0.61 | HTT (0.60) | MAPTNPC1RAB9AHTTTHRB | |
| SCHEMBL27035133 | 0.61 | MAPT (0.65) | ALDH1A1MAPTNPC1RAB9AHTT | |
| SCHEMBL27035097 | 0.61 | TSHR (0.57) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024019685-A2 | NOVEL 3,5-DISUBSTITUTED-1,2,4-OXADIAZOLE DERIVED COMPOUNDS AND INHIBITORY ACTIVITY OF THESE COMPOUNDS ON CARBONIC ANHYDRASE I AND II ENZYMES | ANADOLU UNIVERSITESI (TR) | 2024-01-25 | — | — | WO | claimed |