Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27059728 | 0.88 | GPR119 (0.47) | PARP1MAPTHTT | |
| SCHEMBL30769828 | 0.88 | GPR119 (0.47) | PARP1MAPTHTT | |
| SCHEMBL27059727 | 0.88 | GPR119 (0.47) | PARP1MAPTHTT | |
| SCHEMBL27035226 | 0.88 | GPR119 (0.47) | PARP1MAPTHTT | |
| SCHEMBL30769925 | 0.88 | GPR119 (0.47) | PARP1MAPTHTT | |
| SCHEMBL30769850 | 0.84 | PARP1 (0.41) | PARP1MAPK7SMN1; SMN2MAPTPOLB | |
| SCHEMBL27059735 | 0.84 | MAPK7 (0.47) | PARP1MAPK7HTR2B | |
| SCHEMBL27055200 | 0.84 | MAPK7 (0.47) | PARP1MAPK7HTR2B | |
| SCHEMBL27055206 | 0.84 | MAPK7 (0.47) | PARP1MAPK7HTR2B | |
| SCHEMBL30769737 | 0.82 | PARP1 (0.43) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017977-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-01-25 | — | — | WO | disclosed |