SCHEMBL30769737

SCHEMBL30769737

CO[C@H]1CC[C@@H](c2nc3c(C4CCNCC4)ccnc3[nH]2)CC1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PARP1 P09874 5/20 0.43
▸ CDK9 P50750 10/20 0.39
▸ CDK1 P06493 1/20 0.39
▸ CCNT1 O60563 9/20 0.38
▸ HTR6 P50406 2/20 0.37
▸ HTR1A P08908 1/20 0.36
▸ SLC6A2 P23975 1/20 0.36
▸ SLC6A4 P31645 1/20 0.36
▸ SLC6A3 Q01959 1/20 0.36
▸ HTR2C P28335 1/20 0.35
▸ PBK Q96KB5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27035372 1.00 PARP1 (0.43) PARP1CDK9CDK1CCNT1HTR6
SCHEMBL27059733 1.00 PARP1 (0.43) PARP1CDK9CDK1CCNT1HTR6
Hydrochloric Acid SCHEMBL27035360 0.99 PARP1 (0.42) PARP1CDK9CDK1CCNT1HTR6
SCHEMBL24683422 0.90 PARP1 (0.41) PARP1CDK9CDK1CCNT1HTR6
SCHEMBL29845257 0.90 PARP1 (0.41) PARP1CDK9CDK1CCNT1HTR6
SCHEMBL30769850 0.82 PARP1 (0.41) PARP1
SCHEMBL30769931 0.82 PARP1 (0.41) PARP1CDK9CCNT1HTR6HTR1A
SCHEMBL27035288 0.82 PARP1 (0.41) PARP1CDK9CCNT1HTR6HTR1A
SCHEMBL27035497 0.82 PARP1 (0.45) PARP1
SCHEMBL29845331 0.81 CDK9 (0.40) PARP1CDK9CDK1CCNT1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI-AVENTIS RECHERCHE & DÉVELOPPEMENT (FR) 2026-01-22 — — US disclosed
EP-4558500-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF Sanofi (FR) 2025-05-28 — — EP disclosed
WO-2024017977-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI (FR) 2024-01-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF MAPK1, MAPK3, MAPK6 PARP1 2161/4885CDK9 419/4885CDK1 291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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