Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30769925 | 1.00 | GPR119 (0.47) | GPR119HPGDSPDE10ADDB1CRBN | |
| SCHEMBL30769828 | 1.00 | GPR119 (0.47) | GPR119HPGDSPDE10ADDB1CRBN | |
| SCHEMBL27059727 | 1.00 | GPR119 (0.47) | GPR119HPGDSPDE10ADDB1CRBN | |
| SCHEMBL27035226 | 1.00 | GPR119 (0.47) | GPR119HPGDSPDE10ADDB1CRBN | |
| SCHEMBL24683439 | 0.94 | HPGDS (0.48) | GPR119HPGDSPDE10ADDB1CRBN | |
| SCHEMBL27059725 | 0.90 | HPGDS (0.46) | GPR119HPGDSPDE10ADDB1CRBN | |
| SCHEMBL27035302 | 0.90 | HPGDS (0.46) | GPR119HPGDSPDE10ADDB1CRBN | |
| SCHEMBL27035383 | 0.88 | HPGDS (0.45) | GPR119HPGDSPDE10ADDB1CRBN | |
| SCHEMBL27035497 | 0.88 | PARP1 (0.45) | PARP1MAPTHTT | |
| SCHEMBL30769878 | 0.86 | CCNT1 (0.46) | GPR119HPGDSPDE10ADDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017977-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-01-25 | — | — | WO | disclosed |