SCHEMBL27039

SCHEMBL27039

O=C1CCc2cc(Br)ccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.59
CASP7 P55210 1/20 0.59
HSD17B10 Q99714 1/20 0.59
PARP10 Q53GL7 1/20 0.56
PARP11 Q9NR21 1/20 0.56
SRD5A1 P18405 2/20 0.55
SRD5A2 P31213 1/20 0.55
HSD17B1 P14061 2/20 0.52
GRM5 P41594 1/20 0.49
METAP1 P53582 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TDP2 O95551 1/20 0.47
S100A4 P26447 1/20 0.46
MAOA P21397 2/20 0.46
MAOB P27338 2/20 0.46
TYMS P04818 1/20 0.46
PRKCI P41743 1/20 0.46
CYP11B1 P15538 3/20 0.45
CYP11B2 P19099 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31108080 1.00 CASP1 (0.59) CASP1CASP7HSD17B10PARP10PARP11
SCHEMBL2065611 0.88 MAOA (0.59) CASP1CASP7HSD17B10PARP10PARP11
SCHEMBL29521431 0.88 MAOA (0.59) CASP1CASP7HSD17B10PARP10PARP11
SCHEMBL207834 0.88 MAOA (0.61) CASP1CASP7HSD17B10PARP10PARP11
SCHEMBL570706 0.88 MAOA (0.59) CASP1CASP7HSD17B10PARP10PARP11
SCHEMBL7839573 0.84 TDP1 (0.63) PARP10PARP11SRD5A1SRD5A2METAP1
SCHEMBL31268305 0.84 SRD5A1 (0.64) PARP10PARP11SRD5A1SRD5A2METAP1
SCHEMBL204100 0.84 SRD5A1 (0.64) PARP10PARP11SRD5A1SRD5A2METAP1
SCHEMBL29804236 0.83 PBRM1 (0.64) CASP1CASP7HSD17B10PARP10PARP11
SCHEMBL27286 0.83 PBRM1 (0.64) CASP1CASP7HSD17B10PARP10PARP11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1685 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115417816-B Preparation method of 3, 6-dibromo-1-chloro-isoquinoline 江苏南大光电材料股份有限公司 2024-01-26 CN claimed
CN-115650886-A Oxime sulfonate photoacid generators and use of resist compositions 瑞红(苏州)电子化学品股份有限公司 2023-01-31 CN claimed
CN-115572262-A Isoquinoline derivative and preparation method thereof 厦门沃克沃德医药科技有限公司 2023-01-06 CN claimed
CN-113861113-B Preparation and application of fused ring pyridine compound and derivative thereof 中国科学院福建物质结构研究所 2022-12-06 CN claimed
CN-115417816-A Preparation method of 3,6-dibromo-1-chloro-isoquinoline 江苏南大光电材料股份有限公司 2022-12-02 CN claimed
CN-110240537-B Indene oxyacetic acid compound and preparation method and application thereof 成都阿奇生物医药科技有限公司 2022-06-21 CN claimed
CN-110590642-B Electroluminescent material with indenone as electron acceptor and its application 大连理工大学 2022-06-07 CN claimed
CN-114163301-A Preparation method of benzo [ B ] fluorene derivative and derivative thereof 陕西维世诺新材料有限公司 2022-03-11 CN claimed
CN-113861113-A Preparation and application of fused ring pyridine compound and derivative thereof 中国科学院福建物质结构研究所 2021-12-31 CN claimed
CN-113321617-A Red light thermal induction delay fluorescent material, preparation method thereof and organic electroluminescent device 中国科学院长春应用化学研究所 2021-08-31 CN claimed
CN-110615783-B Electroluminescent material with pyrazinoindenone as electron acceptor and application thereof 大连理工大学 2021-04-20 CN claimed
CN-112574078-A 2-sulfuryl-2, 3-dihydro-1-indanone and derivatives and synthesis method thereof 湖南工程学院 2021-03-30 CN claimed
CN-109569730-B Catalyst and application thereof 江苏师范大学 2021-01-22 CN claimed
CN-110615783-A Electroluminescent material with pyrazinoindenone as electron acceptor and application thereof 大连理工大学 2019-12-27 CN claimed
CN-110590642-A Electroluminescent material with indenone as electron acceptor and its application 大连理工大学 2019-12-20 CN claimed
US-10092786-B2 Fire extinguishing composition comprising aldoketones compound XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-10-09 US claimed
US-20160332016-A1 Fire Extinguishing Composition Comprising Aldoketones Compound NANO FIRE, LLC 2016-11-17 US claimed
US-5618982-A SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES RHONE-POULENC CHIMIE (FR) 1997-04-08 US claimed
US-20260146035-A1 FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS DONG-A ST CO., LTD. (KR) 2026-05-28 US disclosed
US-4738972-A Hypoglycemic thiazolidinediones PFIZER INC. (US) 1988-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146035-A1 FUSED BICYCLIC COMPOUNDS AND THEIR USE AS MER AND AXL INHIBITORS AXL, ERBB2, ERBB3 CASP1 1376/4885CASP7 2522/4885HSD17B10 4424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.