Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2836768 | 0.93 | BBOX1 (0.57) | BBOX1KMT2AATMALDH1A1ACHE | |
| Bicarbonate SCHEMBL5911592 | 0.93 | BBOX1 (0.57) | BBOX1KMT2AATMALDH1A1ACHE | |
| Bicarbonate SCHEMBL2704202 | 0.90 | BBOX1 (0.59) | BBOX1KMT2AATMALDH1A1ACHE | |
| Acrylic Acid SCHEMBL27587559 | 0.90 | LMNA (0.50) | BBOX1KMT2AATMALDH1A1ACHE | |
| Acrylic Acid SCHEMBL28444109 | 0.87 | LMNA (0.48) | BBOX1KMT2AATMALDH1A1ACHE | |
| Acrylic Acid SCHEMBL20983701 | 0.87 | LMNA (0.48) | BBOX1KMT2AATMALDH1A1ACHE | |
| Succinic Acid SCHEMBL28710004 | 0.87 | BBOX1 (0.52) | BBOX1KMT2AATMALDH1A1ACHE | |
| Maleic Acid SCHEMBL9664934 | 0.87 | BBOX1 (0.47) | BBOX1KMT2AATMALDH1A1ACHE | |
| Acrylic Acid SCHEMBL1356182 | 0.87 | LMNA (0.48) | BBOX1KMT2AATMALDH1A1ACHE | |
| Glyoxylate SCHEMBL27749644 | 0.87 | BBOX1 (0.47) | BBOX1KMT2AATMALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104857867-B | CO2 separating membrane having both primary amine and carbonate and preparation method thereof | 天津大学 | 2017-04-26 | — | — | CN | claimed |
| CN-104857867-A | Carbon dioxide separating membrane having both primary amine and carbonate and preparation method thereof | UNIV TIANJIN | 2015-08-26 | — | — | CN | claimed |
| US-20120107415-A1 | COMBINED DISINFECTION AND DECONTAMINATION AGENT HAVING INCREASED EFFECTIVENESS | MULTIBIND BIOTEC GMBH (DE) | 2012-05-03 | — | — | US | claimed |
| EP-3497435-B1 | INORGANIC ION DETECTION SYSTEM AND METHODS | UNIV TASMANIA (AU) | 2023-07-12 | — | — | EP | disclosed |
| CN-109716122-B | Inorganic ion detection system and method | 塔斯马尼亚大学 | 2022-06-24 | — | — | CN | disclosed |
| US-20190353614-A1 | INORGANIC ION DETECTION SYSTEM AND METHODS | UNIVERSITY OF TASMANIA (AU) | 2019-11-21 | — | — | US | disclosed |
| EP-3497435-A1 | INORGANIC ION DETECTION SYSTEM AND METHODS | University Of Tasmania (AU) | 2019-06-19 | — | — | EP | disclosed |
| WO-2018032043-A1 | INORGANIC ION DETECTION SYSTEM AND METHODS | UNIVERSITY OF TASMANIA (AU) | 2018-02-22 | — | — | WO | disclosed |
| CN-104857867-B | CO2 separating membrane having both primary amine and carbonate and preparation method thereof | 天津大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-104857867-B | CO2 separating membrane having both primary amine and carbonate and preparation method thereof | 天津大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-104857867-A | Carbon dioxide separating membrane having both primary amine and carbonate and preparation method thereof | UNIV TIANJIN | 2015-08-26 | — | — | CN | disclosed |
| CN-104857867-A | Carbon dioxide separating membrane having both primary amine and carbonate and preparation method thereof | UNIV TIANJIN | 2015-08-26 | — | — | CN | disclosed |
| US-8999399-B2 | Combined disinfection and decontamination agent having increased effectiveness | Bose Chemie GmbH (DE) | 2015-04-07 | — | — | US | disclosed |
| US-20120107415-A1 | COMBINED DISINFECTION AND DECONTAMINATION AGENT HAVING INCREASED EFFECTIVENESS | MULTIBIND BIOTEC GMBH (DE) | 2012-05-03 | — | — | US | disclosed |
| WO-2008035101-A2 | DISINFECTANT EMULSIONS CONTAINING AN ANTIMICROBIAL COMPOUND IN EACH PHASE | MAINSANI AS (NO) | 2008-03-27 | — | — | WO | disclosed |