SCHEMBL270428

SCHEMBL270428

C=C(C)C(=O)c1ccc(N=Nc2ccc(C(=O)C(=C)C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.57
NPC1 O15118 6/20 0.53
RAB9A P51151 6/20 0.53
MAPK1 P28482 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
STAT3 P40763 1/20 0.53
STAT1 P42224 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
KDM4E B2RXH2 1/20 0.48
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
TRPA1 O75762 1/20 0.47
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270427 1.00 MAPT (0.57) MAPTNPC1RAB9AMAPK1SMN1; SMN2
SCHEMBL27947436 0.92 TRPA1 (0.60) MAPTNPC1RAB9AMAPK1SMN1; SMN2
SCHEMBL28670034 0.86 MAPT (0.71) MAPTSMN1; SMN2THRATHRBMEN1
SCHEMBL18937072 0.85 MAPT (0.44) MAPTNPC1RAB9AMAPK1SMN1; SMN2
SCHEMBL29730046 0.83 MAPT (0.48) MAPTNPC1RAB9AMAPK1SMN1; SMN2
SCHEMBL9297911 0.82 RAB9A (0.47) MAPTNPC1RAB9AMAPK1SMN1; SMN2
SCHEMBL6272776 0.77 MAPT (0.61) MAPTSMN1; SMN2THRATHRBMEN1
SCHEMBL5852775 0.77 MAPT (0.61) MAPTTHRATHRBMEN1KMT2A
SCHEMBL2401025 0.77 MAPT (0.61) MAPTSMN1; SMN2TDP1THRATHRB
SCHEMBL2816739 0.77 CES2 (0.68) MAPTNPC1RAB9AMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170160593-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-08 US disclosed
US-20170160593-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-08 US disclosed
EP-1773485-B1 STABLE COMPOSITE MATERIAL COMPRISING SUPPORTED POROUS GELS NATRIX SEPARATIONS INC (CA) 2015-09-16 EP disclosed
EP-1758671-B9 MEMBRANE STACKS NATRIX SEPARATIONS INC (CA) 2014-02-19 EP disclosed
US-8652849-B2 Method for separating a substance from a fluid NATRIX SEPARATIONS INC. (CA) 2014-02-18 US disclosed
EP-1758671-B1 MEMBRANE STACKS NATRIX SEPARATIONS INC (CA) 2013-09-04 EP disclosed
US-8383782-B2 Composite materials comprising supported porous gels NATRIX SEPARATIONS INC. (CA) 2013-02-26 US disclosed
US-8367809-B2 Composite materials comprising supported porous gels containing reactive functional groups NATRIX SEPARATIONS INC. (CA) 2013-02-05 US disclosed
US-8313651-B2 Membrane stacks NATRIX SEPARATIONS INC. (CA) 2012-11-20 US disclosed
US-8211682-B2 Composite material comprising supported porous gel containing functional groups and method of separating substances NATRIX SEPARATIONS INC. (CA) 2012-07-03 US disclosed
US-20090029438-A1 COMPOSITE MATERIALS COMPRISING SUPPORTED POROUS GELS MERCK MILLIPORE LTD. (IE) 2009-01-29 US disclosed
US-20090008328-A1 Composite Materials Comprising Supported Porous Gels NATRIX SEPARATIONS INC. (CA) 2009-01-08 US disclosed
US-20080314831-A1 Composite Materials Comprising Supported Porous Gels NYSA MEMBRANCE TECHNOLOGIES INC. (CA) 2008-12-25 US disclosed
US-20080312416-A1 Composite Materials Comprising Supported Porous Gels NYSA MEMBRANE TECHNOLOGIES INC. (CA) 2008-12-18 US disclosed
US-20080264867-A1 Stable Composite Material Comprising Supported Porous Gels NYSA MEMBRANE TECHNOLOGIES INC. 2008-10-30 US disclosed
US-20080017578-A1 Membrane Stacks MERCK MILLIPORE LTD. (IE) 2008-01-24 US disclosed
US-7316919-B2 Composite materials comprising supported porous gels NYSA MEMBRANE TECHNOLOGIES (CA) 2008-01-08 US disclosed
EP-1773485-A1 STABLE COMPOSITE MATERIAL COMPRISING SUPPORTED POROUS GELS McMaster University (CA) 2007-04-18 EP disclosed
WO-2005120701-A1 STABLE COMPOSITE MATERIAL COMPRISING SUPPORTED POROUS GELS MCMASTER UNIVERSITY (CA) 2005-12-22 WO disclosed
US-20040203149-A1 Composite materials comprising supported porous gels MERCK MILLIPORE LTD. (IE) 2004-10-14 US disclosed