Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | STAT3 | P40763 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | FLT3 | P36888 | 6/20 | 0.61 |
| ▸ | CDK2 | P24941 | 2/20 | 0.61 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.61 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.60 |
| ▸ | WNT1 | P04628 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.56 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7429480 | 0.96 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP1A2YTHDC1KDM4ESTAT3 | |
| SCHEMBL8714399 | 0.85 | HTT (0.74) | SMN1; SMN2CYP1A2YTHDC1KDM4ESTAT3 | |
| SCHEMBL31571485 | 0.85 | KDM4E (0.58) | SMN1; SMN2CYP1A2YTHDC1KDM4ESTAT3 | |
| SCHEMBL18851945 | 0.84 | YTHDC1 (0.61) | SMN1; SMN2CYP1A2YTHDC1KDM4ESTAT3 | |
| SCHEMBL19884728 | 0.83 | YTHDC1 (0.59) | SMN1; SMN2CYP1A2YTHDC1KDM4ESTAT3 | |
| SCHEMBL2723267 | 0.82 | YTHDC1 (1.00) | SMN1; SMN2YTHDC1KDM4ESTAT3HIF1A | |
| SCHEMBL30036108 | 0.82 | YTHDC1 (1.00) | SMN1; SMN2YTHDC1KDM4ESTAT3HIF1A | |
| SCHEMBL31445444 | 0.80 | YTHDC1 (0.59) | SMN1; SMN2YTHDC1KDM4ESTAT3HIF1A | |
| SCHEMBL954045 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2YTHDC1KDM4ESTAT3HIF1A | |
| SCHEMBL38655498 | 0.79 | YTHDC1 (0.71) | SMN1; SMN2YTHDC1KDM4ESTAT3HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112673000-B | 1H-indazole carboxamides as receptor interacting protein kinase 1 inhibitors (RIPK 1) | 百时美施贵宝公司 | 2024-10-18 | — | — | CN | claimed |
| EP-4037772-B1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-11-22 | — | — | EP | claimed |
| EP-3849968-B1 | 1H-INDAZOLE CARBOXAMIDES AS RECEPTOR-INTERACTING PROTEIN KINASE 1 INHIBITORS (RIPK1) | BRISTOL MYERS SQUIBB CO (US) | 2022-12-21 | — | — | EP | claimed |
| WO-2024109642-A1 | USE OF BENZOAZACYCLIC COMPOUND AS ALLOSTERIC MODULATOR OF β2-ADRENOCEPTOR | 常州大学 | 2024-05-30 | — | — | WO | disclosed |
| CN-117229217-A | Allosteric modulator of adrenergic receptor functional activity, preparation method and application thereof | 常州大学 | 2023-12-15 | — | — | CN | disclosed |
| US-8088562-B2 | Heat sensitive ; coating hydrophilic support with hydrophobic thermoplastic resin; photopolymerization using photoinitiator; exposure; heating;development; antideposit agents | AGFA GRAPHICS NV (BE) | 2012-01-03 | — | — | US | disclosed |
| US-8088562-B2 | Heat sensitive ; coating hydrophilic support with hydrophobic thermoplastic resin; photopolymerization using photoinitiator; exposure; heating;development; antideposit agents | AGFA GRAPHICS NV (BE) | 2012-01-03 | — | — | US | disclosed |
| US-20090017398-A1 | METHOD FOR MAKING A LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2009-01-15 | — | — | US | disclosed |
| US-20090017398-A1 | METHOD FOR MAKING A LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2009-01-15 | — | — | US | disclosed |
| EP-1902044-A1 | 5-HTX MODULATORS | Bio Medisinsk Innovasjon AS (NO) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007099053-A1 | METHOD FOR MAKING A LITHOGRAPHIC PRINTING PLATE | AGFA GRAPHICS NV (BE) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007007072-A1 | 5-HTX MODULATORS | BIO-MEDISINSK INNOVASJON AS (NO) | 2007-01-18 | — | — | WO | disclosed |