Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | FLT3 | P36888 | 4/20 | 0.55 |
| ▸ | CDK2 | P24941 | 2/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714399 | 0.88 | HTT (0.74) | YTHDC1KDM4ESMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL2704442 | 0.84 | SMN1; SMN2 (0.71) | YTHDC1KDM4ESMN1; SMN2FLT3CDK2 | |
| Oxalic Acid SCHEMBL7429480 | 0.81 | SMN1; SMN2 (0.66) | YTHDC1KDM4ESMN1; SMN2FLT3CDK2 | |
| SCHEMBL19884728 | 0.80 | YTHDC1 (0.59) | YTHDC1KDM4ESMN1; SMN2FLT3CDK2 | |
| SCHEMBL38655498 | 0.79 | YTHDC1 (0.71) | YTHDC1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL2021679 | 0.79 | YTHDC1 (0.71) | YTHDC1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL18851649 | 0.78 | YTHDC1 (0.51) | YTHDC1KDM4ESMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL18851928 | 0.78 | YTHDC1 (0.51) | YTHDC1KDM4ESMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL18851943 | 0.78 | YTHDC1 (0.51) | YTHDC1KDM4ESMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL18851791 | 0.78 | YTHDC1 (0.51) | YTHDC1KDM4ESMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170129892-A1 | TRICYCLIC COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129892-A1 | TRICYCLIC COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | CHRNA7, CHRNA6, CHRNA5 | YTHDC1 4807/4885KDM4E 4148/4885SMN1; SMN2 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.