Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045230 | 0.85 | PTGS2 (0.53) | VCPALDH1A1ACHEPTGDR2PTGS2 | |
| SCHEMBL27049017 | 0.83 | ACHE (0.41) | ALDH1A1HTTACHENPY5RPTGDR2 | |
| SCHEMBL27045229 | 0.83 | ACHE (0.46) | VCPALDH1A1HTTACHENPY5R | |
| SCHEMBL27045227 | 0.80 | ACHE (0.44) | VCPALDH1A1ACHEPTGDR2PTGS2 | |
| SCHEMBL27045233 | 0.78 | KMT2A (0.50) | VCPALDH1A1HTTNPY5RALOX5 | |
| SCHEMBL27045226 | 0.76 | ACHE (0.39) | VCPALDH1A1HTTACHENPY5R | |
| SCHEMBL27045236 | 0.76 | PTGDR2 (0.42) | ALDH1A1HTTPTGDR2PKMGAA | |
| SCHEMBL27045812 | 0.74 | EGLN2 (0.42) | ALDH1A1HTTPTGDR2PKMPTGS2 | |
| SCHEMBL27045589 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HTTPTGDR2PKMPTGS2 | |
| SCHEMBL27045699 | 0.70 | PTGDR2 (0.43) | ALDH1A1HTTPTGDR2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |