Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | XIAP | P98170 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045499 | 0.91 | PTGS2 (0.56) | PTGS2PTGDR2MAPTALDH1A1MEN1 | |
| SCHEMBL27045449 | 0.90 | PTGS2 (0.47) | PTGS2PTGDR2MAPTALDH1A1MEN1 | |
| SCHEMBL27045986 | 0.85 | PTGS2 (0.43) | PTGS2PTGDR2MAPTALDH1A1MEN1 | |
| SCHEMBL27045515 | 0.82 | PTGS2 (0.46) | PTGS2PTGDR2MAPTALDH1A1MEN1 | |
| SCHEMBL27045443 | 0.82 | PTGS2 (0.48) | PTGS2PTGDR2MAPTALDH1A1MEN1 | |
| SCHEMBL27046007 | 0.82 | PTGS2 (0.41) | PTGS2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27045504 | 0.81 | ALDH1A1 (0.45) | PTGS2PTGDR2MAPTALDH1A1MEN1 | |
| SCHEMBL27045568 | 0.81 | MAPT (0.53) | PTGS2PTGDR2MAPTALDH1A1MEN1 | |
| SCHEMBL27046261 | 0.78 | PTGS2 (0.48) | PTGS2PTGDR2MAPTALDH1A1MEN1 | |
| SCHEMBL27045988 | 0.77 | PTGS2 (0.56) | PTGS2PTGDR2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |