Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.40 |
| ▸ | XIAP | P98170 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045686 | 0.90 | PTGS2 (0.40) | PTGS2PTGDR2XIAPALDH1A1PKM | |
| SCHEMBL27045590 | 0.89 | PTGS2 (0.46) | PTGS2PTGDR2XIAPALDH1A1KMT2A | |
| SCHEMBL27045988 | 0.88 | PTGS2 (0.56) | PTGS2PTGDR2XIAPALDH1A1KMT2A | |
| SCHEMBL27045496 | 0.85 | PTGS2 (0.48) | PTGS2PTGDR2XIAPALDH1A1KMT2A | |
| SCHEMBL27046007 | 0.84 | PTGS2 (0.41) | PTGS2XIAPALDH1A1PKMKMT2A | |
| SCHEMBL27045699 | 0.81 | PTGDR2 (0.43) | PTGDR2ALDH1A1PKMFFAR1KMT2A | |
| SCHEMBL27045983 | 0.81 | PTGS2 (0.43) | PTGS2PTGDR2XIAPALDH1A1PKM | |
| SCHEMBL27049755 | 0.80 | PTGS2 (0.36) | PTGS2XIAPALDH1A1PKMACHE | |
| SCHEMBL27045683 | 0.79 | PTGS2 (0.45) | PTGS2PTGDR2XIAPALDH1A1KMT2A | |
| SCHEMBL27045689 | 0.78 | PTGS2 (0.51) | PTGS2PTGDR2XIAPALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |