Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045579 | 0.93 | SMN1; SMN2 (0.71) | SMN1; SMN2MAPK1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL18674588 | 0.89 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPK1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL27045809 | 0.88 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPK1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL27046977 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPK1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL3451243 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL27045507 | 0.84 | RAB9A (0.53) | SMN1; SMN2MAPK1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL27049484 | 0.84 | RAB9A (0.53) | SMN1; SMN2MAPK1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL2228768 | 0.81 | RAB9A (0.57) | SMN1; SMN2ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL18674669 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL12805634 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2MAPK1ALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |