Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | AR | P10275 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045579 | 0.90 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9AL3MBTL1NPC1MAPK1 | |
| SCHEMBL27045697 | 0.88 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9AL3MBTL1NPC1MAPK1 | |
| SCHEMBL27049855 | 0.81 | L3MBTL1 (0.58) | SMN1; SMN2RAB9AL3MBTL1NPC1MAPK1 | |
| SCHEMBL3765693 | 0.78 | LMNA (0.72) | SMN1; SMN2RAB9AL3MBTL1NPC1MAPK1 | |
| SCHEMBL27046977 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AL3MBTL1NPC1MAPK1 | |
| SCHEMBL2555802 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AL3MBTL1NPC1MAPK1 | |
| SCHEMBL27045807 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9AL3MBTL1NPC1MAPK1 | |
| SCHEMBL2228768 | 0.77 | RAB9A (0.57) | SMN1; SMN2RAB9AL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL28548975 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AL3MBTL1NPC1MAPK1 | |
| SCHEMBL18674588 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AL3MBTL1NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-B1 | EIF4E INHIBITORS AND USES THEREOF | PIC THERAPEUTICS INC (US) | 2024-01-24 | — | — | EP | disclosed |