Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722547 | 0.71 | AKR1C1 (0.57) | OPRL1HSD11B1 | |
| SCHEMBL501923 | 0.71 | AKR1C1 (0.57) | OPRL1HSD11B1 | |
| Hydrochloric Acid SCHEMBL1804765 | 0.69 | AKR1C1 (0.55) | OPRL1HSD11B1 | |
| SCHEMBL5106245 | 0.69 | LMNA (0.45) | LMNAALOX5OPRL1HRH3HSD11B1 | |
| SCHEMBL27714872 | 0.69 | LMNA (0.45) | LMNAALOX5OPRL1SYKHRH3 | |
| SCHEMBL518528 | 0.69 | ESR2 (0.45) | LMNAALOX5OPRL1HRH3HSD11B1 | |
| SCHEMBL3951279 | 0.69 | — | — | |
| SCHEMBL2142746 | 0.69 | — | — | |
| SCHEMBL2130769 | 0.68 | OPRL1 (0.44) | LMNAALOX5OPRL1HSD11B1 | |
| SCHEMBL1975025 | 0.68 | HSD11B1 (0.56) | LMNAOPRL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448944-A2 | ISOMANNIDE DERIVATIVES AND THEIR USE AS TASTANTS | Senomyx, Inc. (US) | 2012-05-09 | — | — | EP | disclosed |