Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598009 | 0.66 | DGAT1 (0.34) | LMNAMAPTHTTKMT2APYCR1 | |
| SCHEMBL782593 | 0.63 | LMNA (0.46) | MEN1LMNAMAPTHTTKMT2A | |
| SCHEMBL782594 | 0.63 | DGAT1 (0.34) | CHRM5PTGFRPTGESMEN1LMNA | |
| SCHEMBL1310477 | 0.63 | DGAT1 (0.39) | LMNAPYCR1 | |
| SCHEMBL2274534 | 0.62 | CASP1 (0.39) | MEN1MAPTKMT2APYCR1 | |
| SCHEMBL2274536 | 0.62 | CASP1 (0.39) | MEN1MAPTKMT2APYCR1 | |
| SCHEMBL18494712 | 0.61 | TAAR1 (0.40) | MEN1LMNAMAPTHTTKMT2A | |
| SCHEMBL30350650 | 0.61 | DGAT1 (0.36) | LMNAMAPTPYCR1 | |
| SCHEMBL19510781 | 0.61 | DGAT1 (0.36) | LMNAMAPTPYCR1 | |
| SCHEMBL2274543 | 0.61 | DGAT1 (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435410-A2 | LXR MODULATORS | Exelixis Patent Company LLC (US) | 2012-04-04 | — | — | EP | disclosed |
| WO-2010138598-A2 | LXR MODULATORS | EXELIXIS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |