Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706128 | 0.95 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNACA12CA9 | |
| SCHEMBL2707013 | 0.88 | CA12 (0.51) | ALDH1A1KDM4ELMNACA12CA9 | |
| SCHEMBL3700257 | 0.87 | LMNA (0.50) | ALDH1A1KDM4ELMNACA12CA9 | |
| Acrylic Acid Ethyl Ester SCHEMBL2708956 | 0.86 | CA12 (0.51) | ALDH1A1KDM4ELMNACA12CA9 | |
| SCHEMBL2706218 | 0.84 | CYP3A4 (0.41) | ALDH1A1KDM4ELMNAMAPTPOLB | |
| SCHEMBL2707312 | 0.82 | LMNA (0.50) | ALDH1A1KDM4ELMNACA12CA9 | |
| Acrylic Acid Ethyl Ester SCHEMBL2707955 | 0.81 | CA12 (0.48) | ALDH1A1KDM4ELMNACA12CA9 | |
| SCHEMBL482619 | 0.81 | CYP3A4 (0.50) | ALDH1A1KDM4ELMNAMAPTESR1 | |
| SCHEMBL8166266 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNACA12CA9 | |
| SCHEMBL7199350 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447291-B1 | HIGH-MOLECULAR-WEIGHT COPOLYMER | NIPPON SODA CO (JP) | 2015-04-08 | — | — | EP | disclosed |
| US-8729187-B2 | High-molecular-weight copolymer | NIPPON SODA CO., LTD. (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20120123076-A1 | HIGH-MOLECULAR-WEIGHT COPOLYMER | NIPPON SODA CO., LTD (JP) | 2012-05-17 | — | — | US | disclosed |
| EP-2447291-A1 | HIGH-MOLECULAR-WEIGHT COPOLYMER | Nippon Soda Co., Ltd. (JP) | 2012-05-02 | — | — | EP | disclosed |