SCHEMBL2707186

SCHEMBL2707186

CC1CCCC(C)(C)C1CCC(=O)O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 8/20 0.51
CYP1A2 P05177 1/20 0.38
CDC25A P30304 2/20 0.35
CETP P11597 1/20 0.33
FOLH1 Q04609 1/20 0.33
OPRM1 P35372 1/20 0.32
PTPN1 P18031 1/20 0.32
DUSP3 P51452 1/20 0.32
LMNA P02545 1/20 0.31
BLM P54132 1/20 0.31
GPBAR1 Q8TDU6 1/20 0.31
ALOX5 P09917 1/20 0.31
USP2 O75604 1/20 0.30
FFAR3 O14843 1/20 0.30
CYP2C9 P11712 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2706121 0.90 UGT2B7 (0.53) UGT2B7CYP1A2CDC25ALMNABLM
SCHEMBL1149570 0.86 UGT2B7 (0.38) UGT2B7CYP1A2CETPPTPN1
SCHEMBL28905336 0.85 UGT2B7 (0.38) UGT2B7CYP1A2CETPPTPN1
SCHEMBL2708700 0.84 UGT2B7 (0.40) UGT2B7LMNA
SCHEMBL813797 0.83 UGT2B7 (0.37) UGT2B7CDC25ACETPPTPN1DUSP3
SCHEMBL8050175 0.82 CYP1A2 (0.40) UGT2B7CYP1A2CDC25APTPN1DUSP3
SCHEMBL8050172 0.82 CYP1A2 (0.40) UGT2B7CYP1A2CDC25APTPN1DUSP3
SCHEMBL8050170 0.82 CYP1A2 (0.40) UGT2B7CYP1A2CDC25APTPN1DUSP3
SCHEMBL14850614 0.82 UGT2B7 (0.36) UGT2B7CDC25ACETPPTPN1DUSP3
SCHEMBL813842 0.82 UGT2B7 (0.36) UGT2B7CDC25ACETPPTPN1DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140194651-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN S.A. (CH) 2014-07-10 US claimed
CN-101652342-B Organic compound for masking unpleasant feeling GIVAUDAN SA 2014-01-29 CN claimed
US-8409649-B2 Off-note blocking sensory organic compounds GIVAUDAN S.A. (CH) 2013-04-02 US claimed
EP-2139841-B1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2012-05-02 EP claimed
US-20100284944-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2010-11-11 US claimed
CN-101652342-A Organic compound for masking unpleasant feeling GIVAUDAN SA CH 2010-02-17 CN claimed
EP-2139841-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS Givaudan SA (CH) 2010-01-06 EP claimed
WO-2008119196-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2008-10-09 WO claimed
US-20200345049-A1 COMPOSITIONS GIVAUDAN SA (CH) 2020-11-05 US disclosed
US-9451784-B2 Off-note blocking sensory organic compounds GIVAUDAN S.A. (CH) 2016-09-27 US disclosed
US-9451784-B2 Off-note blocking sensory organic compounds GIVAUDAN S.A. (CH) 2016-09-27 US disclosed
US-9451784-B2 Off-note blocking sensory organic compounds GIVAUDAN S.A. (CH) 2016-09-27 US disclosed
US-20140194651-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN S.A. (CH) 2014-07-10 US disclosed
US-20140194651-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN S.A. (CH) 2014-07-10 US disclosed
US-20100284944-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2010-11-11 US disclosed
US-20100284944-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2010-11-11 US disclosed
CN-101652342-A Organic compound for masking unpleasant feeling GIVAUDAN SA CH 2010-02-17 CN disclosed
EP-2139841-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS Givaudan SA (CH) 2010-01-06 EP disclosed
WO-2008119196-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2008-10-09 WO disclosed
WO-2008119196-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2008-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100284944-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS SORD, OTC, ASPH UGT2B7 1959/4885CYP1A2 3689/4885CDC25A 4113/4885
US-20140194651-A1 OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS SORD, OTC, ASPH UGT2B7 1959/4885CYP1A2 3689/4885CDC25A 4113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.