Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 5/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707186 | 0.90 | UGT2B7 (0.51) | UGT2B7CDC25ACYP1A2ALOX5HSD17B10 | |
| SCHEMBL28679355 | 0.87 | UGT2B7 (0.41) | UGT2B7CDC25A | |
| SCHEMBL2463622 | 0.84 | UGT2B7 (0.39) | UGT2B7CDC25A | |
| SCHEMBL2465723 | 0.82 | UGT2B7 (0.40) | UGT2B7 | |
| SCHEMBL2706965 | 0.81 | ALDH1A1 (0.40) | UGT2B7CYP1A2ALDH1A1NR1I2TSHR | |
| SCHEMBL1149570 | 0.80 | UGT2B7 (0.38) | UGT2B7CYP1A2ALDH1A1 | |
| SCHEMBL8050170 | 0.80 | CYP1A2 (0.40) | UGT2B7CDC25ACYP1A2CYP2C9 | |
| SCHEMBL8050172 | 0.80 | CYP1A2 (0.40) | UGT2B7CDC25ACYP1A2CYP2C9 | |
| SCHEMBL8050175 | 0.80 | CYP1A2 (0.40) | UGT2B7CDC25ACYP1A2CYP2C9 | |
| SCHEMBL7939563 | 0.80 | UGT2B7 (0.49) | UGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140194651-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2014-07-10 | — | — | US | claimed |
| CN-101652342-B | Organic compound for masking unpleasant feeling | GIVAUDAN SA | 2014-01-29 | — | — | CN | claimed |
| US-8409649-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2013-04-02 | — | — | US | claimed |
| EP-2139841-B1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2012-05-02 | — | — | EP | claimed |
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | US | claimed |
| CN-101652342-A | Organic compound for masking unpleasant feeling | GIVAUDAN SA CH | 2010-02-17 | — | — | CN | claimed |
| EP-2139841-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | Givaudan SA (CH) | 2010-01-06 | — | — | EP | claimed |
| WO-2008119196-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-09 | — | — | WO | claimed |
| EP-4138574-A1 | COMPOSITIONS | Givaudan SA (CH) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021214008-A1 | COMPOSITIONS | GIVAUDAN SA (CH) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021214008-A1 | COMPOSITIONS | GIVAUDAN SA (CH) | 2021-10-28 | — | — | WO | disclosed |
| US-20200345049-A1 | COMPOSITIONS | GIVAUDAN SA (CH) | 2020-11-05 | — | — | US | disclosed |
| US-20200345049-A1 | COMPOSITIONS | GIVAUDAN SA (CH) | 2020-11-05 | — | — | US | disclosed |
| US-9451784-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2016-09-27 | — | — | US | disclosed |
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | US | disclosed |
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | US | disclosed |
| CN-101652342-A | Organic compound for masking unpleasant feeling | GIVAUDAN SA CH | 2010-02-17 | — | — | CN | disclosed |
| EP-2139841-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | Givaudan SA (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008119196-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119196-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | SORD, OTC, ASPH | UGT2B7 1959/4885CDC25A 4113/4885CYP1A2 3689/4885 |
| US-20140194651-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | SORD, OTC, ASPH | UGT2B7 1959/4885CDC25A 4113/4885CYP1A2 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.