Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4999938 | 0.94 | CRHBP (0.34) | TDP1ALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL30254595 | 0.85 | TDP1 (0.49) | TDP1ALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL80422 | 0.85 | TDP1 (0.49) | TDP1ALDH1A1KMT2AMEN1CRHBP | |
| SCHEMBL2233605 | 0.73 | — | — | |
| SCHEMBL8665764 | 0.71 | MYC (0.47) | ALDH1A1KMT2AMEN1MAPTPKM | |
| SCHEMBL8668434 | 0.71 | SMN1; SMN2 (0.45) | TDP1ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL490742 | 0.69 | NPC1 (0.53) | TDP1ALDH1A1KMT2AMEN1PIN1 | |
| SCHEMBL8664750 | 0.68 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL2451533 | 0.68 | EGFR (0.39) | ALDH1A1RAB9AMAPTKDM4E | |
| SCHEMBL490715 | 0.68 | AKR1C3 (0.46) | ALDH1A1KMT2AMEN1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447780-A1 | Method for preparation of lithographic printing plate | Fujifilm Corporation (JP) | 2012-05-02 | — | — | EP | disclosed |