Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751513 | 0.79 | ALOX15 (0.39) | ALOX15ALDH1A1CYP3A4TDP1DUSP3 | |
| SCHEMBL933394 | 0.78 | ALOX15 (0.39) | ALOX15ALDH1A1CYP3A4TDP1 | |
| SCHEMBL17223658 | 0.77 | ALOX15 (0.43) | ALOX15ALDH1A1CYP3A4TDP1DUSP3 | |
| SCHEMBL24459467 | 0.76 | ALOX15 (0.44) | ALOX15ALDH1A1CYP3A4TDP1DUSP3 | |
| SCHEMBL1844934 | 0.74 | ALOX15 (0.49) | ALOX15ALDH1A1CYP3A4TDP1 | |
| SCHEMBL20610516 | 0.74 | ALOX15 (0.49) | ALOX15ALDH1A1CYP3A4TDP1 | |
| SCHEMBL4078385 | 0.73 | ALOX15 (0.40) | ALOX15ALDH1A1CYP3A4TDP1 | |
| SCHEMBL31502596 | 0.72 | ALOX15 (0.42) | ALOX15ALDH1A1CYP3A4TDP1DUSP3 | |
| SCHEMBL8656171 | 0.72 | ALOX15 (0.47) | ALOX15ALDH1A1CYP3A4TDP1 | |
| SCHEMBL31502586 | 0.72 | ALOX15 (0.39) | ALOX15ALDH1A1CYP3A4TDP1DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9451784-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2016-09-27 | — | — | US | claimed |
| US-20140194651-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2014-07-10 | — | — | US | claimed |
| US-8409649-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2013-04-02 | — | — | US | claimed |
| EP-2139841-B1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2012-05-02 | — | — | EP | claimed |
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | US | claimed |
| EP-2139841-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | Givaudan SA (CH) | 2010-01-06 | — | — | EP | claimed |
| WO-2008119196-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-09 | — | — | WO | claimed |
| US-20200345049-A1 | COMPOSITIONS | GIVAUDAN SA (CH) | 2020-11-05 | — | — | US | disclosed |
| US-20200345049-A1 | COMPOSITIONS | GIVAUDAN SA (CH) | 2020-11-05 | — | — | US | disclosed |
| US-9451784-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2016-09-27 | — | — | US | disclosed |
| US-9451784-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2016-09-27 | — | — | US | disclosed |
| US-9451784-B2 | Off-note blocking sensory organic compounds | GIVAUDAN S.A. (CH) | 2016-09-27 | — | — | US | disclosed |
| US-20140194651-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2014-07-10 | — | — | US | disclosed |
| EP-2139841-B1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2012-05-02 | — | — | EP | disclosed |
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | US | disclosed |
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | US | disclosed |
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2010-11-11 | — | — | US | disclosed |
| EP-2139841-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | Givaudan SA (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008119196-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119196-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100284944-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | SORD, OTC, ASPH | ALOX15 3836/4885ALDH1A1 2230/4885CYP3A4 2318/4885 |
| US-20140194651-A1 | OFF-NOTE BLOCKING SENSORY ORGANIC COMPOUNDS | SORD, OTC, ASPH | ALOX15 3836/4885ALDH1A1 2230/4885CYP3A4 2318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.