Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL2707239

C=CC(=O)OC.Oc1cccc(C=CC=Cc2ccccc2)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.51
CDK1 P06493 1/20 0.51
CDK4 P11802 1/20 0.51
CCNB1 P14635 1/20 0.51
CCND1 P24385 1/20 0.51
CCNB3 Q8WWL7 1/20 0.51
MMP1 P03956 8/20 0.49
MMP2 P08253 8/20 0.49
MMP9 P14780 8/20 0.49
AKR1B10 O60218 1/20 0.45
AKR1B1 P15121 1/20 0.45
P4HB P07237 1/20 0.45
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45
CYP19A1 P11511 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
ABL1 P00519 1/20 0.44
BCR P11274 1/20 0.44
KDM1A O60341 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL2707868 0.88 CA12 (0.57) MMP1MMP2MMP9AKR1B10AKR1B1
SCHEMBL2708958 0.85 CCNB2 (0.48) CCNB2CDK1CDK4CCNB1CCND1
Acrylic Acid Ethyl Ester SCHEMBL2706416 0.85 AKR1B10 (0.48) CCNB2CDK1CDK4CCNB1CCND1
Acrylic Acid Methyl Ester SCHEMBL1856229 0.84 HDAC3 (0.46) MMP1MMP2MMP9MAOAMAOB
Acrylic Acid Methyl Ester SCHEMBL27395677 0.83 HDAC3 (0.45) MMP1MMP2MMP9MAOAMAOB
Resorcinol SCHEMBL27645965 0.83 ALDH1A1 (0.46) MMP1MMP2MMP9P4HBCYP2C9
Juarezic Acid SCHEMBL9719424 0.82 HDAC3 (0.53) MAOAMAOBHDAC1HDAC6
SCHEMBL2707945 0.82 CCNB2 (0.50) CCNB2CDK1CDK4CCNB1CCND1
Phenol SCHEMBL11827525 0.81 CA12 (0.47) MAOAMAOBCYP2C9CYP2C19
Phenol SCHEMBL27502578 0.81 CA12 (0.47) MAOAMAOBCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2447291-B1 HIGH-MOLECULAR-WEIGHT COPOLYMER NIPPON SODA CO (JP) 2015-04-08 EP disclosed
US-8729187-B2 High-molecular-weight copolymer NIPPON SODA CO., LTD. (JP) 2014-05-20 US disclosed
US-20120123076-A1 HIGH-MOLECULAR-WEIGHT COPOLYMER NIPPON SODA CO., LTD (JP) 2012-05-17 US disclosed
EP-2447291-A1 HIGH-MOLECULAR-WEIGHT COPOLYMER Nippon Soda Co., Ltd. (JP) 2012-05-02 EP disclosed