Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 6/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 6/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TAF1 | P21675 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27074418 | 0.86 | ABCG2 (0.43) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL27075664 | 0.85 | ZAP70 (0.44) | ZAP70NEK2EPHB4PIM1PIM2 | |
| SCHEMBL27074407 | 0.85 | CSNK2A1 (0.46) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL27074406 | 0.83 | IDO1 (0.42) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL27074420 | 0.83 | TNNI3K (0.46) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL27074405 | 0.83 | PIM1 (0.52) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL27074419 | 0.82 | PIM1 (0.50) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL27092619 | 0.82 | EPHB4 (0.45) | NEK2EPHB4PIM1PIM2CSNK2A1 | |
| SCHEMBL27074414 | 0.80 | KDM1A (0.39) | ZAP70CHEK1CYP3A4 | |
| SCHEMBL27074415 | 0.79 | JAK2 (0.38) | ZAP70PIM1PIM2CSNK2A1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884670-B1 | Pyrido[4′,3′:4,5]pyrrolo[3,2-c][2,7]naphthyridin-10-one compounds as CK2 inhibitors | King Faisal University (SA) | 2024-01-30 | — | — | US | claimed |
| US-11884670-B1 | Pyrido[4′,3′:4,5]pyrrolo[3,2-c][2,7]naphthyridin-10-one compounds as CK2 inhibitors | King Faisal University (SA) | 2024-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884670-B1 | Pyrido[4′,3′:4,5]pyrrolo[3,2-c][2,7]naphthyridin-10-one compounds as CK2 inhibitors | CKS2, CDK2, PNKP | ZAP70 476/4885NEK2 191/4885EPHB4 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.