Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27074418 | 0.86 | ABCG2 (0.43) | JAK2CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL27074407 | 0.85 | CSNK2A1 (0.46) | MAPTHTTJAK2SMN1; SMN2RAB9A | |
| SCHEMBL27075661 | 0.84 | TNNI3K (0.46) | TNNI3KALDH1A1KDM4EGAAMAPT | |
| SCHEMBL27074406 | 0.83 | IDO1 (0.42) | JAK2CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL27074413 | 0.83 | ZAP70 (0.42) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL27074405 | 0.83 | PIM1 (0.52) | ALDH1A1CSNK2A2CSNK2BCSNK2A1PIM1 | |
| SCHEMBL27074419 | 0.82 | PIM1 (0.50) | MAPTHTTMEN1LMNAKMT2A | |
| SCHEMBL27092630 | 0.82 | ALDH1A1 (0.47) | TNNI3KALDH1A1KDM4EGAAMAPT | |
| SCHEMBL27074414 | 0.80 | KDM1A (0.39) | KDM4EGAAMAPTJAK2JAK1 | |
| SCHEMBL27074410 | 0.79 | LATS1 (0.42) | ALDH1A1KDM4EMAPTHTTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884670-B1 | Pyrido[4′,3′:4,5]pyrrolo[3,2-c][2,7]naphthyridin-10-one compounds as CK2 inhibitors | King Faisal University (SA) | 2024-01-30 | — | — | US | claimed |
| US-11884670-B1 | Pyrido[4′,3′:4,5]pyrrolo[3,2-c][2,7]naphthyridin-10-one compounds as CK2 inhibitors | King Faisal University (SA) | 2024-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884670-B1 | Pyrido[4′,3′:4,5]pyrrolo[3,2-c][2,7]naphthyridin-10-one compounds as CK2 inhibitors | CKS2, CDK2, PNKP | TNNI3K 130/4885ALDH1A1 4535/4885KDM4E 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.