Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 7/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 7/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 13/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 9/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 9/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27171394 | 0.84 | EPHB4 (0.47) | EPHB4CSNK2A1NEK2 | |
| SCHEMBL27092631 | 0.83 | ABCG2 (0.48) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL27199805 | 0.83 | EPHB4 (0.45) | EPHB4PIM1PIM2CSNK2A1CSNK2A2 | |
| SCHEMBL27215998 | 0.82 | PIM1 (0.46) | EPHB4PIM1PIM2CSNK2A1CSNK2A2 | |
| SCHEMBL27074413 | 0.82 | ZAP70 (0.42) | EPHB4PIM1PIM2CSNK2A1CSNK2A2 | |
| SCHEMBL27092627 | 0.81 | LATS1 (0.52) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL27182128 | 0.81 | CSNK2A1 (0.51) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL27092630 | 0.81 | ALDH1A1 (0.47) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL31356294 | 0.80 | EPHB4 (0.47) | EPHB4PIM1PIM2CSNK2A1CSNK2A2 | |
| SCHEMBL27092629 | 0.79 | PIM1 (0.58) | PIM1PIM2CSNK2A1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12240851-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-c]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-03-04 | — | — | US | claimed |
| US-20250066362-A1 | PYRIDO[3',4':4,5]PYRROLO[3,2-C]NAPHTHYRIDINE COMPOUNDS AS CK2 INHIBITORS | King Faisal University (SA) | 2025-02-27 | — | — | US | claimed |
| US-11905289-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-C]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-02-20 | — | — | US | claimed |
| US-12240851-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-c]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-03-04 | — | — | US | disclosed |
| US-20250066362-A1 | PYRIDO[3',4':4,5]PYRROLO[3,2-C]NAPHTHYRIDINE COMPOUNDS AS CK2 INHIBITORS | King Faisal University (SA) | 2025-02-27 | — | — | US | disclosed |
| US-11905289-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-C]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2024-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066362-A1 | PYRIDO[3',4':4,5]PYRROLO[3,2-C]NAPHTHYRIDINE COMPOUNDS AS CK2 INHIBITORS | CKS2, CDK2, PNKP | EPHB4 2834/4885PIM1 540/4885PIM2 348/4885 |
| US-12240851-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-c]naphthyridine compounds as CK2 inhibitors | CKS2, CDK2, PNKP | EPHB4 2783/4885PIM1 555/4885PIM2 356/4885 |
| US-11905289-B1 | Pyrido[3′,4′:4,5]pyrrolo[3,2-C]naphthyridine compounds as CK2 inhibitors | CKS2, CDK2, PNKP | EPHB4 2783/4885PIM1 555/4885PIM2 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.