Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24259829 | 0.78 | SLC22A6 (0.43) | LMNATDP1ALDH1A1MAPTPTGS2 | |
| SCHEMBL18818920 | 0.76 | TDP1 (0.45) | LMNATDP1ALDH1A1MAPTPTGS2 | |
| SCHEMBL27468494 | 0.73 | HIF1A (0.42) | LMNATDP1HIF1ASLC22A6GABRR1 | |
| SCHEMBL11414379 | 0.73 | SMN1; SMN2 (0.52) | LMNATDP1MAPTHIF1ASLC22A6 | |
| SCHEMBL3328326 | 0.73 | — | — | |
| SCHEMBL5819782 | 0.73 | HIF1A (0.42) | LMNATDP1HIF1ASLC22A6GABRR1 | |
| SCHEMBL1372611 | 0.73 | HIF1A (0.42) | LMNATDP1HIF1ASLC22A6GABRR1 | |
| SCHEMBL26742365 | 0.73 | ALDH1A1 (0.47) | LMNATDP1ALDH1A1MAPTPTGS2 | |
| SCHEMBL21518545 | 0.72 | — | — | |
| SCHEMBL13697033 | 0.71 | HIF1A (0.40) | LMNATDP1ALDH1A1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240036042-A1 | CLICK CHEMISTRY AMPLIFIED NANOPORE ASSAY FOR ULTRASENSITIVE QUANTIFICATION OF PROTEINS | NATIONAL SCIENCE FOUNDATION | 2024-02-01 | — | — | US | disclosed |