Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 2/20 | 0.52 |
| ▸ | TDO2 | P48775 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27075647 | 0.85 | BUB1 (0.53) | BUB1MAPK14MEN1KMT2AABL1 | |
| SCHEMBL27075640 | 0.84 | IDO1 (0.50) | BUB1TDO2IDO1ERBB2PTK6 | |
| SCHEMBL27075644 | 0.82 | BUB1 (0.55) | BUB1TDO2IDO1 | |
| SCHEMBL27075636 | 0.82 | KDM1A (0.48) | BUB1ERBB2EGFR | |
| SCHEMBL27075654 | 0.80 | MAPK1 (0.48) | CHUKMAPK13RAF1MAPK12MAPK11 | |
| SCHEMBL27075633 | 0.78 | MEN1 (0.52) | KDM4ECHUKPIM1MEN1KMT2A | |
| SCHEMBL27075652 | 0.78 | BUB1 (0.46) | BUB1KDM4EMEN1KMT2A | |
| SCHEMBL27075646 | 0.73 | BUB1 (0.52) | BUB1TDO2IDO1KDM4ECHUK | |
| SCHEMBL4785768 | 0.72 | FADS1 (0.71) | TDO2IDO1PIM1PIM2FADS1 | |
| SCHEMBL27215791 | 0.71 | PIM1 (0.51) | KDM4EERBB2PTK6PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891390-B1 | 3-substituted amino-2-arylpyrrolo[2,3-c]pyridines as CK2 inhibitors | King Faisal University (SA) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891390-B1 | 3-substituted amino-2-arylpyrrolo[2,3-c]pyridines as CK2 inhibitors | CSNK2A3, CSNK2A2, CSNK2A1 | BUB1 407/4885TDO2 427/4885IDO1 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.