Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.46 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | ABL2 | P42684 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 3/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27075653 | 0.84 | IDO1 (0.53) | IDO1TDO2ERBB2PIM1EGFR | |
| SCHEMBL27075643 | 0.84 | BUB1 (0.52) | IDO1TDO2ERBB2PTK6PIM1 | |
| SCHEMBL27075637 | 0.82 | IGF1R (0.45) | EIF2AK2EGFRCHUKROCK2 | |
| SCHEMBL27075647 | 0.70 | BUB1 (0.53) | ABL1BCRBUB1PTGS1PTGS2 | |
| SCHEMBL4785768 | 0.69 | FADS1 (0.71) | IDO1TDO2PIM1PIM2FADS1 | |
| SCHEMBL27075642 | 0.69 | CHUK (0.45) | IDO1TDO2PIM1PRKCAPRKCD | |
| SCHEMBL27075648 | 0.69 | CHUK (0.45) | IDO1TDO2PIM1CHUK | |
| SCHEMBL27215791 | 0.68 | PIM1 (0.51) | ERBB2PTK6PIM1PIM2EGFR | |
| SCHEMBL13051120 | 0.68 | ABL1 (0.58) | EIF2AK2EGFRABL1BCRPRKCA | |
| SCHEMBL3949696 | 0.68 | HTR3E (0.59) | IDO1TDO2ERBB2EGFRFADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891390-B1 | 3-substituted amino-2-arylpyrrolo[2,3-c]pyridines as CK2 inhibitors | King Faisal University (SA) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891390-B1 | 3-substituted amino-2-arylpyrrolo[2,3-c]pyridines as CK2 inhibitors | CSNK2A3, CSNK2A2, CSNK2A1 | IDO1 1592/4885TDO2 427/4885ERBB2 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.