Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 4/20 | 0.38 |
| ▸ | CPT1A | P50416 | 3/20 | 0.36 |
| ▸ | CPT2 | P23786 | 2/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPIG | Q13427 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709286 | 0.88 | PPID (0.39) | AADATCPT1ACPT2CPT1BPPID | |
| SCHEMBL2708134 | 0.86 | MEN1 (0.40) | AADATCPT1ACPT2CPT1BNPC1 | |
| SCHEMBL2724717 | 0.84 | NPC1 (0.37) | AADATCPT1ACPT2CPT1BNPC1 | |
| SCHEMBL2139189 | 0.80 | AHR (0.42) | AADATNPC1RAB9A | |
| SCHEMBL2708567 | 0.78 | DPP4 (0.42) | AADATNPC1RAB9APOLBPREP | |
| SCHEMBL2138294 | 0.69 | MAOA (0.35) | AADATPREPDPP4FAP | |
| SCHEMBL2139572 | 0.69 | AHR (0.40) | AADATPREP | |
| SCHEMBL2137255 | 0.69 | NPSR1 (0.43) | NPC1ALDH1A1 | |
| SCHEMBL2139149 | 0.69 | MAOA (0.37) | AADATNPC1RAB9A | |
| SCHEMBL7364621 | 0.68 | ACE (0.62) | RAB9AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447265-A1 | NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2012-05-02 | — | — | EP | disclosed |