Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2708134 | 0.86 | MEN1 (0.40) | NPC1RAB9APOLBCPT2CPT1A | |
| SCHEMBL2708567 | 0.85 | DPP4 (0.42) | NPC1RAB9APOLBAADAT | |
| SCHEMBL2707642 | 0.84 | AADAT (0.38) | NPC1RAB9APOLBCPT2CPT1A | |
| SCHEMBL2709286 | 0.81 | PPID (0.39) | CPT2CPT1ACPT1BAADAT | |
| SCHEMBL5648347 | 0.72 | AADAT (0.42) | NPC1RAB9ACPT2CPT1ACPT1B | |
| SCHEMBL5648354 | 0.72 | AADAT (0.42) | NPC1RAB9ACPT2CPT1ACPT1B | |
| SCHEMBL15270350 | 0.70 | POLB (0.41) | NPC1RAB9APOLBRIPK1CPT2 | |
| SCHEMBL2707575 | 0.69 | PRKAB2 (0.38) | NOTUM | |
| SCHEMBL29481542 | 0.68 | RIPK1 (0.45) | NPC1RAB9ARIPK1HSP90AA1HSP90AB1 | |
| SCHEMBL5645605 | 0.68 | TRPV1 (0.46) | RAB9APOLBCPT2CPT1ACPT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447265-A1 | NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2012-05-02 | — | — | EP | disclosed |