Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 8/20 | 0.39 |
| ▸ | PREP | P48147 | 6/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | PPIG | Q13427 | 5/20 | 0.36 |
| ▸ | PPIB | P23284 | 4/20 | 0.36 |
| ▸ | FAP | Q12884 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2707642 | 0.88 | AADAT (0.38) | PPIDPREPAADATPPIGFAP | |
| SCHEMBL2708134 | 0.83 | MEN1 (0.40) | AADATLMNACPT2CPT1ACPT1B | |
| SCHEMBL2724717 | 0.81 | NPC1 (0.37) | AADATCPT2CPT1ACPT1B | |
| SCHEMBL2139572 | 0.81 | AHR (0.40) | PREPAADATPPIB | |
| SCHEMBL2138294 | 0.81 | MAOA (0.35) | PREPAADATFAPDPP4 | |
| SCHEMBL2708567 | 0.77 | DPP4 (0.42) | PREPAADATFAPDPP4 | |
| SCHEMBL2139057 | 0.75 | HSD17B10 (0.44) | AADATLMNA | |
| SCHEMBL2139189 | 0.69 | AHR (0.42) | AADAT | |
| SCHEMBL2139149 | 0.66 | MAOA (0.37) | AADAT | |
| SCHEMBL2136123 | 0.65 | DPP4 (0.30) | FAPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447265-A1 | NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2012-05-02 | — | — | EP | disclosed |