SCHEMBL2707650

SCHEMBL2707650

Cc1ccc(C2=Cc3c(cccc3-c3ccc(C(C)(C)C)cc3)C2)o1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.35
CREBBP Q92793 1/20 0.35
S1PR1 P21453 1/20 0.32
GSK3B P49841 3/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
GNRHR P30968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15827724 0.86 PTGS1 (0.37) BRD4CREBBPGSK3BNPC1LMNA
SCHEMBL16333088 0.83 GSK3B (0.37) BRD4CREBBPGSK3B
SCHEMBL2238185 0.81 NQO2 (0.31) NPC1RAB9A
SCHEMBL29594761 0.79 BRD4 (0.36) BRD4CREBBPS1PR1NPC1LMNA
SCHEMBL1807786 0.79 BRD4 (0.36) BRD4CREBBPS1PR1NPC1LMNA
SCHEMBL29040664 0.77 BRD4 (0.36) BRD4CREBBPS1PR1NPC1LMNA
Lithium SCHEMBL30438304 0.77 BRD4 (0.36) BRD4CREBBPS1PR1NPC1LMNA
SCHEMBL28148566 0.77 BRD4 (0.36) BRD4CREBBPS1PR1NPC1LMNA
SCHEMBL17060058 0.76
Hydrochloric Acid SCHEMBL27911650 0.76 KIF11 (0.36) BRD4CREBBPS1PR1NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438183-B1 POLYETHYLENE AND MOLDED BODY THEREOF JAPAN POLYETHYLENE CORP (JP) 2023-11-22 EP disclosed
CN-108884282-B Polyethylene and molded article thereof 日本聚乙烯株式会社 2021-06-08 CN disclosed
US-20190136021-A1 POLYETHYLENE AND MOLDED BODY THEREOF JAPAN POLYETHYLENE CORPORATION (JP) 2019-05-09 US disclosed
EP-3438183-A1 POLYETHYLENE AND MOLDED BODY OF SAME Japan Polypropylene Corporation (JP) 2019-02-06 EP disclosed
CN-101772519-B Propylene polymer, process for producing the same, composition containing the same, and use thereof JAPAN POLYPROPYLENE CORP 2012-07-04 CN disclosed
EP-2177544-B1 PROPYLENE POLYMER, PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING THE SAME, AND USE THEREOF JAPAN POLYPROPYLENE CORP (JP) 2012-05-02 EP disclosed
US-8080624-B2 Propylene-based polymer, production method therefor, composition using the same, and application thereof JAPAN POLYPROPYLENE CORPORATION (JP) 2011-12-20 US disclosed
US-20100227987-A1 PROPYLENE-BASED POLYMER, PRODUCTION METHOD THEREFOR, COMPOSITION USING THE SAME, AND APPLICATION THEREOF JAPAN POLYPROPYLENE CORPORATION (JP) 2010-09-09 US disclosed
CN-101772519-A Propylene polymer, process for producing the same, composition containing the same, and use thereof JAPAN POLYPROPYLENE CORP 2010-07-07 CN disclosed
EP-2177544-A1 PROPYLENE POLYMER, PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING THE SAME, AND USE THEREOF Japan Polypropylene Corporation (JP) 2010-04-21 EP disclosed