Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | ITGAL | P20701 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508253 | 0.83 | PIN1 (0.38) | ITGB2ICAM1ITGALPIN1KMT2A | |
| SCHEMBL31734675 | 0.81 | ACE (0.39) | MMEACE | |
| SCHEMBL10937069 | 0.80 | PIN1 (0.39) | ITGB2ICAM1ITGALPIN1KMT2A | |
| SCHEMBL10937082 | 0.80 | PIN1 (0.39) | ITGB2ICAM1ITGALPIN1KMT2A | |
| SCHEMBL304609 | 0.77 | ITGA4 (0.39) | ITGA4ITGB7MMETACR1PIN1 | |
| SCHEMBL753950 | 0.77 | ITGA4 (0.41) | ITGA4ITGB7MMEITGB2ICAM1 | |
| SCHEMBL304610 | 0.77 | ITGA4 (0.39) | ITGA4ITGB7MMETACR1PIN1 | |
| SCHEMBL8412037 | 0.74 | FDPS (0.40) | KMT2A | |
| SCHEMBL1539193 | 0.73 | SLC7A5 (0.45) | KMT2ACYP2C19MEN1 | |
| SCHEMBL1641338 | 0.73 | SLC7A5 (0.45) | KMT2ACYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435429-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-04-04 | — | — | EP | disclosed |
| WO-2010138488-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-12-02 | — | — | WO | disclosed |