Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2136387 | 0.76 | AHR (0.42) | ALDH1A1MAOA | |
| SCHEMBL2707575 | 0.74 | PRKAB2 (0.38) | MEN1MAPTKMT2A | |
| SCHEMBL2136123 | 0.66 | DPP4 (0.30) | — | |
| SCHEMBL2708087 | 0.65 | DPP4 (0.44) | — | |
| SCHEMBL10397862 | 0.64 | ALDH1A1 (0.48) | KDM4EMEN1ALDH1A1MAPTDAO | |
| SCHEMBL287087 | 0.62 | ALDH1A1 (0.57) | KDM4EMEN1ALDH1A1MAPTDAO | |
| SCHEMBL2724717 | 0.61 | NPC1 (0.37) | ALDH1A1 | |
| SCHEMBL23633781 | 0.59 | CHRNA1 (0.33) | — | |
| SCHEMBL18863638 | 0.59 | CHRNA1 (0.33) | — | |
| SCHEMBL20520605 | 0.59 | KDM4E (0.44) | KDM4EMEN1ALDH1A1MAPTDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2447265-A1 | NOVEL THIOPHENE CARBOXAMIDE DERIVATIVE AND MEDICINAL USE OF SAME | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2012-05-02 | — | — | EP | disclosed |