Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.33 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.33 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.33 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.33 |
| ▸ | SDCBP | O00560 | 1/20 | 0.32 |
| ▸ | SDC2 | P34741 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23725969 | 0.83 | CD274 (0.36) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL27080704 | 0.81 | CD274 (0.37) | PRMT5WDR77CRBNDDB1CD274 | |
| SCHEMBL27080699 | 0.81 | CD274 (0.37) | PRMT5WDR77CRBNDDB1CD274 | |
| SCHEMBL29984636 | 0.79 | SDCBP (0.41) | CSNK1A1SALL4GSPT1IKZF3CRBN | |
| SCHEMBL27080703 | 0.76 | PRMT5 (0.35) | PRMT5WDR77CSNK1A1SALL4GSPT1 | |
| SCHEMBL27080877 | 0.76 | PRMT5 (0.35) | PRMT5WDR77CSNK1A1SALL4GSPT1 | |
| SCHEMBL29984097 | 0.73 | PRMT5 (0.32) | PRMT5WDR77CSNK1A1SALL4GSPT1 | |
| SCHEMBL27081925 | 0.73 | PRMT5 (0.32) | PRMT5WDR77CSNK1A1SALL4GSPT1 | |
| SCHEMBL27080763 | 0.70 | PRMT5 (0.35) | PRMT5WDR77CSNK1A1SALL4GSPT1 | |
| SCHEMBL30434602 | 0.69 | PARP1 (0.45) | PRMT5WDR77SDCBPSDC2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313968-A2 | SUBSTITUTED 1-ARYL-1'-HETEROARYL COMPOUNDS, SUBSTITUTED 1,1'-BIHETEROARYL COMPOUNDS, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2024-02-07 | — | — | EP | disclosed |