SCHEMBL27081237

SCHEMBL27081237

COc1ccc(C(OC[C@H](O)CNC(=O)C(F)(F)F)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ MAPT P10636 3/20 0.45
▸ CYP2D6 P10635 1/20 0.41
▸ ADRB2 P07550 1/20 0.41
▸ ADRB1 P08588 1/20 0.41
▸ ADRB3 P13945 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ KIF11 P52732 3/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ CASR P41180 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8843146 1.00 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1MAPTCYP2D6
SCHEMBL14286694 0.85 NPC1 (0.42) KMT2AMEN1KIF11
SCHEMBL890354 0.83 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1MAPTPOLB
SCHEMBL25598334 0.83 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1MAPTPOLB
SCHEMBL16472145 0.82 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1MAPTPOLB
SCHEMBL25969983 0.82 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1MAPTPOLB
SCHEMBL14847398 0.82 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1MAPTPOLB
SCHEMBL20149858 0.82 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1MAPTPOLB
SCHEMBL8843149 0.82 KMT2A (0.40) ALDH1A1KMT2AMEN1MAPTADRB2
SCHEMBL27081269 0.81 MEN1 (0.38) KMT2AMEN1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209018-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS GENSCRIPT USA INC. 2024-06-27 — — US disclosed
EP-4313984-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS Genscript USA Inc. (US) 2024-02-07 — — EP disclosed
WO-2022204102-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS GENSCRIPT USA INC. (US) 2022-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209018-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS RNGTT, DTYMK, UNG ALDH1A1 4471/4885KMT2A 1002/4885MEN1 2038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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