SCHEMBL27081269

SCHEMBL27081269

COc1ccc(C(OC[C@@H](CNC(=O)C(F)(F)F)O[Si](C)(C)C(C)(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ PSMB5 P28074 1/20 0.37
▸ NQO2 P16083 2/20 0.36
▸ MTNR1A P48039 3/20 0.36
▸ MTNR1B P49286 3/20 0.36
▸ KIF11 P52732 4/20 0.36
▸ SLC6A1 P30531 2/20 0.35
▸ SLC6A11 P48066 1/20 0.35
▸ AHR P35869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27081272 1.00 MEN1 (0.38) MEN1KMT2APSMB5NQO2MTNR1A
SCHEMBL27081364 0.82 KIF11 (0.37) MEN1KMT2AKIF11
SCHEMBL27081368 0.82 KIF11 (0.37) MEN1KMT2AKIF11
SCHEMBL8843146 0.81 ALDH1A1 (0.47) MEN1KMT2AKIF11
SCHEMBL27081237 0.81 ALDH1A1 (0.47) MEN1KMT2AKIF11
SCHEMBL27081257 0.79 KIF11 (0.41) KIF11SLC6A1SLC6A11
SCHEMBL27081261 0.79 KIF11 (0.41) KIF11SLC6A1SLC6A11
SCHEMBL8843117 0.77 KIF11 (0.35) MEN1KMT2ANQO2MTNR1AMTNR1B
SCHEMBL24127770 0.74 MTNR1A (0.41) NQO2MTNR1AMTNR1BKIF11SLC6A1
SCHEMBL8843202 0.73 MTNR1A (0.39) KMT2ANQO2MTNR1AMTNR1BKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209018-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS GENSCRIPT USA INC. 2024-06-27 — — US disclosed
EP-4313984-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS Genscript USA Inc. (US) 2024-02-07 — — EP disclosed
WO-2022204102-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS GENSCRIPT USA INC. (US) 2022-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209018-A1 UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS RNGTT, DTYMK, UNG MEN1 2038/4885KMT2A 1002/4885PSMB5 3551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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