Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5911245 | 0.82 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3SLC7A5ALOX5 | |
| SCHEMBL5911184 | 0.81 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3SLC7A5ALOX5 | |
| SCHEMBL3798593 | 0.78 | CACNA2D1 (0.36) | SLC6A2SLC6A4SLC6A3SLC7A5MLNR | |
| SCHEMBL5911550 | 0.77 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3SLC7A5ALOX5 | |
| SCHEMBL628049 | 0.74 | RAB9A (0.37) | SLC6A2SLC6A4SLC6A3ALOX5MLNR | |
| SCHEMBL1888261 | 0.74 | — | — | |
| SCHEMBL3465862 | 0.74 | — | — | |
| SCHEMBL12261602 | 0.74 | — | — | |
| SCHEMBL11726275 | 0.73 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3SLC7A5ALOX5 | |
| SCHEMBL2880798 | 0.73 | ALOX5 (0.39) | SLC6A2SLC6A4SLC6A3ALOX5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313065-A2 | METHODS AND COMPOSITIONS FOR TREATING CLOSTRIDIODES DIFFICILE INFECTIONS | Matrivax, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |