Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28785571 | 0.91 | LMNA (0.35) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL827372 | 0.87 | ALOX5 (0.35) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL8107643 | 0.87 | ALOX5 (0.39) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL9130249 | 0.87 | ALOX5 (0.39) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL439568 | 0.87 | TAS1R3 (0.36) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL9883154 | 0.84 | SLC6A2 (0.42) | ALOX5CES2CES1KEAP1MAPT | |
| SCHEMBL17787300 | 0.84 | ALOX5 (0.37) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL2887376 | 0.84 | KDM4E (0.44) | ALOX5CES2CES1KEAP1TSHR | |
| SCHEMBL598926 | 0.82 | KDM4E (0.40) | ALOX5TSHRRAB9ANPC1KMT2A | |
| SCHEMBL14777613 | 0.82 | ALOX5 (0.36) | ALOX5CES2CES1KEAP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111408412-B | Catalyst composition, preparation method thereof and application thereof in reaction of synthesizing 1-butene by ethylene selective dimerization | 中国石油化工股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| US-20160008339-A1 | PSORALEN DERIVATIVES FOR PREVENTING OR TREATING HEART FAILURE OR CARDIAC HYPERTROPHY | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2016-01-14 | — | — | US | disclosed |
| US-8754175-B2 | Monocapped conductive polymers with alkenyl or alkynyl end groups and block copolymers therefrom | CARNEGIE MELLON UNIVERSITY (US) | 2014-06-17 | — | — | US | disclosed |
| US-8379369-B2 | Base material for solid electrolytic capacitor, capacitor using the base material, and method for manufacturing the capacitor | MURATA MANUFACTURING CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20120190868-A1 | SUBSTITUTED BENZOCHALCOGENOACENE COMPOUND, THIN FILM COMPRISING THE COMPOUND, AND ORGANIC SEMICONDUCTOR DEVICE INCLUDING THE THIN FILM | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2012-07-26 | — | — | US | disclosed |
| US-7848083-B2 | Solid electrolytic capacitor and method for manufacturing same | MURATA MANUFACTURING CO., LTD. (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20100117030-A1 | Monocapped conductive polymers with alkenyl or alkynyl end groups and block copolymers therefrom | CARNEGIE MELLON UNIVERSITY | 2010-05-13 | — | — | US | disclosed |
| US-20100103589-A1 | BASE MATERIAL FOR SOLID ELECTROLYTIC CAPACITOR, CAPACITOR USING THE BASE MATERIAL, AND METHOD FOR MANUFACTURING THE CAPACITOR | SHOWA DENKO K.K. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20100039751-A1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR MANUFACTURING SAME | SHOWA DENKO K.K. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-7662971-B2 | enzyme inhibitor for treating sleep disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-16 | — | — | US | disclosed |
| US-4260745-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4252950-A | ANTIBIOTICS, BACTERICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4208515-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4065621-A | Process for 3-alkyl and 3-phenyl cephalosporins | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4064343-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4013651-A | 3-SUBSTITUTED AMINO-CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-3992377-A | 3-Thio-substituted cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3985737-A | ANTIBACTERIAL AGENTS | ELI LILLY AND COMPANY (US) | 1976-10-12 | — | — | US | disclosed |
| US-3962227-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008339-A1 | PSORALEN DERIVATIVES FOR PREVENTING OR TREATING HEART FAILURE OR CARDIAC HYPERTROPHY | PAH, P4HA1, NPR3 | ALOX5 296/4885CES2 4295/4885CES1 789/4885 |
| US-20120190868-A1 | SUBSTITUTED BENZOCHALCOGENOACENE COMPOUND, THIN FILM COMPRISING THE COMPOUND, AND ORGANIC SEMICONDUCTOR DEVICE INCLUDING THE THIN FILM | EBPL, SAAL1, APOL1 | ALOX5 2179/4885CES2 642/4885CES1 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.