Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14322129 | 0.88 | HSD17B10 (0.35) | NPSR1HSD17B10MAPT | |
| SCHEMBL4880953 | 0.78 | CYP19A1 (0.56) | CYP19A1DPP4TSHRF2NPSR1 | |
| SCHEMBL27957226 | 0.77 | CYP19A1 (0.42) | CYP19A1HTR2ACYP1A2 | |
| SCHEMBL7009772 | 0.74 | CYP2D6 (0.54) | NPSR1HSD17B10HTR2ATAAR1CYP2D6 | |
| SCHEMBL12770874 | 0.74 | CYP2D6 (0.54) | NPSR1HSD17B10HTR2ATAAR1CYP2D6 | |
| SCHEMBL12770872 | 0.74 | CYP2D6 (0.54) | NPSR1HSD17B10HTR2ATAAR1CYP2D6 | |
| SCHEMBL946807 | 0.74 | TSHR (0.48) | CYP19A1DPP4TSHRF2NPSR1 | |
| SCHEMBL8026290 | 0.74 | TSHR (0.41) | CYP19A1TSHRNPSR1HSD17B10CYP2D6 | |
| Hydrochloric Acid SCHEMBL27915645 | 0.72 | DPP4 (0.46) | DPP4F2HTR2ATAAR1 | |
| SCHEMBL11368289 | 0.69 | CYP17A1 (0.62) | CYP19A1NPSR1HTR2ACYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003282-B | A kind of prepare new derivatives of porphyrin method and purposes as PDT reagent and fluorescent probe | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-01-20 | — | — | CN | claimed |
| CN-103003282-A | A process for the preparation of novel porphyrin derivatives and their use as PDT agents and fluorescence probes | COUNCIL SCIENT IND RES | 2013-03-27 | — | — | CN | claimed |
| CN-105820183-A | Boron dipyrromethene compound containing alpha,beta-unsaturated ketone, and application of same in detection of sulfite | 华东理工大学 | 2016-08-03 | — | — | CN | disclosed |
| CN-103003282-B | A kind of prepare new derivatives of porphyrin method and purposes as PDT reagent and fluorescent probe | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103003282-A | A process for the preparation of novel porphyrin derivatives and their use as PDT agents and fluorescence probes | COUNCIL SCIENT IND RES | 2013-03-27 | — | — | CN | disclosed |
| US-8133474-B2 | Porphyrin chelate compound that may be complexed with zinc, manganese, magnesium, iron or aluminum; capable of insertion into cell; zinc, calcium, mercury, cadmium, and lead analytes; determining shift in signal; medical diagnosis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-13 | — | — | US | disclosed |
| US-20080138292-A1 | Sensors for fluorescence and magnetic resonance imaging | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138292-A1 | Sensors for fluorescence and magnetic resonance imaging | CA2, SLC30A6, SLC39A3 | CYP19A1 3881/4885DPP4 2368/4885TSHR 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.