Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | MPO | P05164 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 5/20 | 0.48 |
| ▸ | HTR1B | P28222 | 5/20 | 0.48 |
| ▸ | SLC5A1 | P13866 | 5/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27085078 | 0.92 | TYR (0.51) | HTR2AMPOATMTYRSLC5A1 | |
| SCHEMBL27084969 | 0.87 | HTR2A (0.61) | HTR2AMPOHTR1DHTR1BHTR1A | |
| SCHEMBL30630407 | 0.87 | HTR2A (0.61) | HTR2AMPOHTR1DHTR1BHTR1A | |
| SCHEMBL29748694 | 0.87 | ATM (0.57) | ATMTYRSLC5A1SLC5A2 | |
| SCHEMBL10400748 | 0.85 | ATM (0.55) | HTR2AATMTYRHTR1DHTR1B | |
| SCHEMBL17967319 | 0.85 | ATM (0.55) | HTR2AATMTYRHTR1DHTR1B | |
| SCHEMBL15902334 | 0.82 | HTR2A (0.56) | HTR2AMPOATMTYRSLC5A1 | |
| SCHEMBL15902786 | 0.82 | HTR2A (0.56) | HTR2AMPOATMTYRSLC5A1 | |
| SCHEMBL26790992 | 0.82 | HTR1D (0.56) | HTR2AMPOATMTYRHTR1D | |
| SCHEMBL27084741 | 0.82 | HTR1D (0.56) | HTR2AMPOATMTYRHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | COMPASS PATHFINDER LIMITED (GB) | 2024-02-08 | — | — | US | disclosed |
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | INMT, AANAT, HNMT | HTR2A 53/4885MPO 117/4885ATM 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.