SCHEMBL2708577

SCHEMBL2708577

CC12CC3CC(C)(C1)CC(c1cc(N)c(O)c(-c4cc(C56CC7CC(C)(CC(C)(C7)C5)C6)cc(N)c4O)c1)(C3)C2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 5/20 0.36
GRIN2A Q12879 5/20 0.36
GRIN2D O15399 4/20 0.36
GRIN3B O60391 4/20 0.36
GRIN2B Q13224 4/20 0.36
GRIN2C Q14957 4/20 0.36
GRIN3A Q8TCU5 4/20 0.36
LMNA P02545 2/20 0.36
PTPN11 Q06124 1/20 0.36
NR0B2 Q15466 1/20 0.36
SLC22A1 O15245 1/20 0.36
ESR1 P03372 1/20 0.36
ADRB3 P13945 1/20 0.36
ACHE P22303 1/20 0.36
OPRK1 P41145 1/20 0.36
MTOR P42345 1/20 0.36
HTT P42858 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2709408 0.79 PTPN11 (0.35) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL2707766 0.78 MEN1 (0.47) LMNAPTPN11EPHX2MEN1KMT2A
SCHEMBL2710995 0.78 PTPN11 (0.37) PTPN11NR0B2EPHX2MEN1KMT2A
SCHEMBL4583150 0.77 GAA (0.44) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL2709923 0.76 MEN1 (0.46) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL17042471 0.75 ACHE (0.40) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL2746765 0.75 EPHX2 (0.34) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL2710150 0.75 ESR1 (0.36) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B
SCHEMBL2709672 0.73 PTPN11 (0.39) PTPN11NR0B2ESR1EPHX2MEN1
SCHEMBL3178486 0.72 ALDH1A1 (0.42) GRIN1GRIN2AGRIN2DGRIN3BGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-7652125-B2 Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed
US-20080255335-A1 Resin Composition, Polyimide Resin Composition, Polybenzoxazole Resin Composition, Varnish, Resin Film and Semiconductor Device Using the Same SUMITOMO BAKELITE COMPANY LTD. (JP) 2008-10-16 US disclosed
EP-1813637-A1 RESIN COMPOSITION, POLYIMIDE RESIN COMPOSITION, POLY- BENZOXAZOLE RESIN COMPOSITION, VARNISHES, RESIN FILMS AND SEMICONDUCTOR DEVICES MADE BY USING THE SAME Sumitomo Bakelite Company, Limited (JP) 2007-08-01 EP disclosed