Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.37 |
| ▸ | SYK | P43405 | 4/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | STK25 | O00506 | 1/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | MUSK | O15146 | 1/20 | 0.35 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30033586 | 1.00 | BRD4 (0.37) | BRD4SYKTYRO3BMPR1BCDC7 | |
| SCHEMBL13425071 | 0.78 | BRD4 (0.36) | BRD4SYKTYRO3BMPR1BCDC7 | |
| Ammonia Solution, Strong SCHEMBL2517930 | 0.76 | SYK (0.42) | BRD4SYKTYRO3BMPR1BCDC7 | |
| SCHEMBL1083288 | 0.74 | SYK (0.62) | BRD4SYKTYRO3BMPR1BCDC7 | |
| SCHEMBL27088248 | 0.73 | PARP1 (0.41) | TYRO3KDRDYRK1BPDE3BPDE3A | |
| SCHEMBL30032265 | 0.73 | PARP1 (0.41) | TYRO3KDRDYRK1BPDE3BPDE3A | |
| SCHEMBL4146597 | 0.71 | BRD4 (0.53) | BRD4SYKTYRO3BMPR1BCDC7 | |
| SCHEMBL16606964 | 0.71 | SYK (0.52) | BRD4SYKTYRO3BMPR1BCDC7 | |
| SCHEMBL29671171 | 0.71 | SYK (0.52) | BRD4SYKTYRO3BMPR1BCDC7 | |
| SCHEMBL29036314 | 0.71 | KDM4E (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226107-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| US-20240226107-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| EP-4321515-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | Simcere Zaiming Pharmaceutical Co., Ltd. (CN) | 2024-02-14 | — | — | EP | disclosed |
| WO-2023245611-A1 | SMALL MOLECULE COMPOUND WITH TTK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川大学华西医院 | 2023-12-28 | — | — | WO | disclosed |
| CN-116462679-A | Pyrazolopyrimidine derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-07-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226107-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | USP1, USP2, USP3 | BRD4 1342/4885SYK 3495/4885TYRO3 4476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.