Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392686 | 0.76 | HDAC6 (0.68) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL13401534 | 0.73 | SMN1; SMN2 (0.67) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL11830543 | 0.72 | ALDH1A1 (0.68) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL10350929 | 0.72 | ALDH1A1 (0.64) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL15731791 | 0.71 | HSD17B10 (0.65) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL13401667 | 0.69 | HDAC3 (0.61) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL11837828 | 0.69 | ALOX15 (0.56) | HPGDALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL20068030 | 0.68 | SIRT2 (0.72) | MAPTMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL1520968 | 0.68 | SMN1; SMN2 (0.57) | MAPTHPGDALDH1A1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL844383 | 0.68 | POLB (0.39) | MAPTHPGDALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240050471-A1 | METHODS FOR ACTIVATING IMMUNE CELLS AND TREATING OCULAR NEOVASCULARIZATION | WASHINGTON UNIVERSITY (US) | 2024-02-15 | — | — | US | disclosed |